Zhilong Jia

I am an Associate Professor in Chinese PLA General Hospital after obtaining a doctor of philosophy degree in Biomedical Engineering. My research interests are drug repositioning and Omics. I developed drug repositioning methods, such as cogena, and applied them into various diseases, such as cardiovascular disease, periodontal disease, mountain sickness and COVID-19.

Selected papers:

2023 Structural variants involved in high-altitude adaptation detected using single-molecule long-read sequencing
- TibetanSV web server
2023 Low-dose of caffeine alleviates high altitude pulmonary edema via regulating mitochondrial quality control process in AT1 cells
2022 Proteomic and clinical biomarkers for acute mountain sickness in a longitudinal cohort
- Reproducible research: code
2021 The active lung microbiota landscape of COVID-19 patients through the metatranscriptome data analysis
- Reproducible research: code
2020 Impacts of the Plateau Environment on the Gut Microbiota and Blood Clinical Indexes in Han and Tibetan Individuals
2020 Transcriptome-based drug repositioning for coronavirus disease 2019 (COVID-19)
- Reproducible research: code
2020 Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients
- Reproducible research (only related to my contributions): code
2019 Time-Course Transcriptome Analysis for Drug Repositioning in Fusobacterium nucleatum-Infected Human Gingival Fibroblasts or PubMed
- Reproducible research: code
2019 Transcriptional profiling in the livers of rats after hypobaric hypoxia exposure.
- Reproducible research: code
2016 Cogena, a novel tool for co-expressed gene-set enrichment analysis, applied to drug repositioning and drug mode of action discovery
- cogena: code or Bioconductor
- Reproducible research: code
2015 Gene Ranking of RNA-Seq Data via Discriminant Non-Negative Matrix Factorization (DNMF)
- DNMF package: CRAN
- Reproducible research: code

Meeting with slides:

Updated Date： 18 Dec., 2023.