2025-04-17-23_articles_updated

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期刊: Nature

标题: 线粒体代谢维持DNMT3A-R882突变克隆性造血

英文标题: Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis

链接: https://www.nature.com/articles/s41586-025-08980-6

期刊: Nature

标题: 马铃薯基因组宝库揭示了关于平凡土豆的秘密

英文标题: What a trove of potato genomes reveals about the humble spud

链接: https://www.nature.com/articles/d41586-025-01247-0

期刊: Nature

标题: 四倍体欧洲马铃薯的阶段性全基因组

英文标题: The phased pan-genome of tetraploid European potato

链接: https://www.nature.com/articles/s41586-025-08843-0

期刊: Nature

标题: 野生和栽培水稻的泛基因组参考

英文标题: A pangenome reference of wild and cultivated rice

链接: https://www.nature.com/articles/s41586-025-08883-6

期刊: Nature

标题: 生成具有代谢功能的成人肝细胞器官体

英文标题: Generation of human adult hepatocyte organoids with metabolic functions

链接: https://www.nature.com/articles/s41586-025-08861-y

期刊: Nature

标题: 深度视觉蛋白质组学绘制遗传性肝病的蛋白质毒性图谱

英文标题: Deep Visual Proteomics maps proteotoxicity in a genetic liver disease

链接: https://www.nature.com/articles/s41586-025-08885-4

期刊: Nature

标题: 与常见糖尿病药物对抗的与年龄相关的血液状况

英文标题: Age-related blood condition counteracted with a common diabetes drug

链接: https://www.nature.com/articles/d41586-025-01129-5

期刊: Computational biology and bioinformatics : nature.com subject feeds

标题: TRAPT:一种基于大规模表观基因组数据预测转录调控因子的多阶段融合深度学习框架

英文标题: TRAPT: a multi-stage fused deep learning framework for predicting transcriptional regulators based on large-scale epigenomic data

链接: https://www.nature.com/articles/s41467-025-58921-0

期刊: Computational biology and bioinformatics : nature.com subject feeds

标题: 四倍体欧洲马铃薯的阶段性全基因组

英文标题: The phased pan-genome of tetraploid European potato

链接: https://www.nature.com/articles/s41586-025-08843-0

期刊: Computational biology and bioinformatics : nature.com subject feeds

标题: 整合批量、单细胞和空间转录组学以识别和功能验证新型靶点,以增强非小细胞肺癌(NSCLC)的免疫治疗

英文标题: Integrating bulk, single-cell, and spatial transcriptomics to identify and functionally validate novel targets to enhance immunotherapy in NSCLC

链接: https://www.nature.com/articles/s41698-025-00893-x

期刊: Nature Reviews Drug Discovery

标题: 回到画板,重新设计无法体验愉悦感的药物

英文标题: Back to the drawing board for anhedonia drugs

链接: https://www.nature.com/articles/d41573-025-00073-3

期刊: Nature Genetics

标题: 基因组分析揭示了苹果属(Malus)的演化和多样性

英文标题: Pan-genome analysis reveals the evolution and diversity of Malus

链接: https://www.nature.com/articles/s41588-025-02166-6

期刊: AAAS: Science Advances: Table of Contents

标题: 饮食中晚期开始限制蛋氨酸促进性别特异性的健康老龄化

英文标题: Dietary methionine restriction started late in life promotes healthy aging in a sex-specific manner

链接: https://www.science.org/doi/abs/10.1126/sciadv.ads1532?af=R

期刊: AAAS: Science Advances: Table of Contents

标题: 一种适用于细菌时间序列成像的多种鲜艳且光稳定单体荧光蛋白调色板

英文标题: A palette of bright and photostable monomeric fluorescent proteins for bacterial time-lapse imaging

链接: https://www.science.org/doi/abs/10.1126/sciadv.ads6201?af=R

期刊: bioRxiv Subject Collection: Bioinformatics

标题: Pangebin:利用全基因组组装图改进细菌分离株的质粒分类

英文标题: Pangebin: improving plasmid binning in bacterial isolates using pangenome-assembly graphs.

链接: https://www.biorxiv.org/content/10.1101/2025.04.10.648291v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: 计算评估植物化学物质作为潜在抗HIV药物针对CCR5和CXCR4受体的作用

英文标题: Computational Evaluation of Phytochemicals as Potential Anti-HIV Drugs Targeting CCR5 and CXCR4 Receptors

链接: https://www.biorxiv.org/content/10.1101/2025.04.10.648243v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: 对单细胞转录组匹配方法进行基准测试,以实现参考图谱的增量增长

英文标题: Benchmarking single cell transcriptome matching methods for incremental growth of reference atlases

链接: https://www.biorxiv.org/content/10.1101/2025.04.10.648034v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: 单细胞转录组中条件间批次效应和生物信号的解耦

英文标题: Disentanglement of batch effects and biological signals across conditions in the single-cell transcriptome

链接: https://www.biorxiv.org/content/10.1101/2025.04.10.648296v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: 从转录组数据和整理的数据库中推断非编码RNA调控网络

英文标题: Inferring non-coding RNA regulatory network from transcriptomic data and curated databases

链接: https://www.biorxiv.org/content/10.1101/2025.04.10.648218v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: 使用Transformer增强的深度学习模型预测3D染色质相互作用

英文标题: Predicting 3D Chromatin Interactions Using Transformer-Enhanced Deep Learning Models

链接: https://www.biorxiv.org/content/10.1101/2025.04.10.647995v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: P Analyze:自动病毒全基因组变异图构建与分析

英文标题: Panalyze: automated virus pangenome variation graph construction and analysis

链接: https://www.biorxiv.org/content/10.1101/2025.04.10.646565v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: 整合多组学和监督学习识别出结直肠癌放疗反应的表皮特征

英文标题: Integrative Multi-omics and Supervised Learning Identifies an Epithelial Signature for Radiotherapy Response in Colorectal Cancer

链接: https://www.biorxiv.org/content/10.1101/2025.04.10.648131v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: sampleclusteR:一个用于使用元数据自动聚类转录组样本的轻量级R包

英文标题: sampleclusteR: A lightweight R package for automated clustering of transcriptomics samples using metadata

链接: https://www.biorxiv.org/content/10.1101/2025.04.10.648129v1?rss=1