2025-04-18-16_articles_updated

期刊: Nature Methods

标题: scMultiSim：基于基因调控网络和细胞间相互作用指导的单细胞多组学和空间数据模拟

英文标题: scMultiSim: simulation of single-cell multi-omics and spatial data guided by gene regulatory networks and cell–cell interactions

链接: https://www.nature.com/articles/s41592-025-02651-0

期刊: Nature Methods

标题: 使用光学显微镜成像3D细胞培养

英文标题: Imaging 3D cell cultures with optical microscopy

链接: https://www.nature.com/articles/s41592-025-02647-w

期刊: Nature

标题: 全基因组测序成功鉴定罕见疾病

英文标题: Whole-genome sequencing susses out rare diseases

链接: https://www.nature.com/articles/d41586-025-01014-1

期刊: Nature Communications

标题: 机器学习特定中心模型在IVF活产预测方面优于基于美国国家登记处的模型

英文标题: Machine learning center-specific models show improved IVF live birth predictions over US national registry-based model

链接: https://www.nature.com/articles/s41467-025-58744-z

期刊: Computational biology and bioinformatics : nature.com subject feeds

标题: 基于微生物基因组向量化的克雷伯菌肺炎亚种的新发致病性特征发现与风险评估

英文标题: De novo virulence feature discovery and risk assessment in Klebsiella pneumoniae based on microbial genome vectorization

链接: https://www.nature.com/articles/s42003-025-07678-9

期刊: Computational biology and bioinformatics : nature.com subject feeds

标题: 在患者来源异种移植基因组分析中评估小鼠污染去除方案的基准测试

英文标题: Benchmarking mouse contamination removing protocols in patient-derived xenografts genomic profiling

链接: https://www.nature.com/articles/s41698-025-00902-z

期刊: Computational biology and bioinformatics : nature.com subject feeds

标题: 药物靶点与人类微生物组代谢组相似性促进药物多效性

英文标题: Similarity of drug targets to human microbiome metaproteome promotes pharmacological promiscuity

链接: https://www.nature.com/articles/s41397-025-00367-0

期刊: Computational biology and bioinformatics : nature.com subject feeds

标题: scMultiSim：基于基因调控网络和细胞间相互作用的单细胞多组学和空间数据模拟

英文标题: scMultiSim: simulation of single-cell multi-omics and spatial data guided by gene regulatory networks and cell–cell interactions

链接: https://www.nature.com/articles/s41592-025-02651-0

期刊: Computational biology and bioinformatics : nature.com subject feeds

标题: 利用新兴测序和深度学习技术发现环状RNA

英文标题: Circular RNA discovery with emerging sequencing and deep learning technologies

链接: https://www.nature.com/articles/s41588-025-02157-7

期刊: Computational biology and bioinformatics : nature.com subject feeds

标题: 颗粒细胞转录受到超排和老龄化的相似影响，并预测早期胚胎轨迹。

英文标题: Granulosa cell transcription is similarly impacted by superovulation and aging and predicts early embryonic trajectories

链接: https://www.nature.com/articles/s41467-025-58451-9

期刊: Nature Genetics

标题: 利用新兴测序和深度学习技术发现环状RNA

英文标题: Circular RNA discovery with emerging sequencing and deep learning technologies

链接: https://www.nature.com/articles/s41588-025-02157-7

期刊: AAAS: Science: Table of Contents

标题: 反复使用复杂结构基因组变异进行适应

英文标题: Adaptation repeatedly uses complex structural genomic variation

链接: https://www.science.org/doi/abs/10.1126/science.adp3745?af=R

期刊: AAAS: Science: Table of Contents

标题: 深组织转录组学和亚细胞高空间分辨率成像

英文标题: Deep-tissue transcriptomics and subcellular imaging at high spatial resolution

链接: https://www.science.org/doi/abs/10.1126/science.adq2084?af=R

期刊: bioRxiv Subject Collection: Bioinformatics

标题: stPipe：一个灵活且高效的R/Bioconductor流程，用于预处理基于测序的的空间转录组学数据

英文标题: stPipe: A flexible and streamlined R/Bioconductor pipeline for preprocessing sequencing-based spatial transcriptomics data

链接: https://www.biorxiv.org/content/10.1101/2025.04.16.649254v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: panomiX：通过多组学数据整合研究性状出现的机制

英文标题: panomiX: Investigating Mechanisms Of Trait Emergence Through Multi-Omics Data Integration

链接: https://www.biorxiv.org/content/10.1101/2025.04.11.648356v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: 全球和跨组学特征聚合提高单细胞多组学整合和聚类

英文标题: Global and cross-omics feature aggregation improves single-cell multi-omics integration and clustering

链接: https://www.biorxiv.org/content/10.1101/2025.04.10.648152v1?rss=1