2025-04-24-16_articles_updated

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期刊: Nature

标题: 一线抗病毒药物对令人担忧的猴痘菌株效果不佳

英文标题: A front-line antiviral drug disappoints against worrisome monkeypox strain

链接: https://www.nature.com/articles/d41586-025-01268-9

期刊: Nature

标题: 原子剥离外延膜以实现无冷却红外检测

英文标题: Atomic lift-off of epitaxial membranes for cooling-free infrared detection

链接: https://www.nature.com/articles/s41586-025-08874-7

期刊: Nature

标题: 微生物代谢物通过ALPK1驱动与衰老相关的克隆性造血

英文标题: Microbial metabolite drives ageing-related clonal haematopoiesis via ALPK1

链接: https://www.nature.com/articles/s41586-025-08938-8

期刊: Nature

标题: 针对PIKfyve驱动的胰腺癌脂质代谢的治疗

英文标题: Targeting PIKfyve-driven lipid metabolism in pancreatic cancer

链接: https://www.nature.com/articles/s41586-025-08917-z

期刊: Nature

标题: 基因组与遗传学对孟德尔豌豆基因的见解

英文标题: Genomic and genetic insights into Mendel’s pea genes

链接: https://www.nature.com/articles/s41586-025-08891-6

期刊: Nature

标题: 空间映射转移性胰腺癌的转录组可塑性

英文标题: Spatial mapping of transcriptomic plasticity in metastatic pancreatic cancer

链接: https://www.nature.com/articles/s41586-025-08927-x

期刊: Nature Reviews Drug Discovery

标题: 加速药物市场注册程序对中国新药审查和批准的影响

英文标题: The impact of accelerated drug marketing registration procedures on the review and approval of new drugs in China

链接: https://www.nature.com/articles/d41573-025-00070-6

期刊: Nature Genetics

标题: 泛基因组分析突出了与栽培性状相关的基因,并提高了苜蓿的基因组辅助育种效果。

英文标题: Pan-genomic analysis highlights genes associated with agronomic traits and enhances genomics-assisted breeding in alfalfa

链接: https://www.nature.com/articles/s41588-025-02164-8

期刊: AAAS: Science Advances: Table of Contents

标题: 揭示角鲨烯代谢的结构解析,揭示了一种优化膜相分离的途径

英文标题: Structural dissection of ergosterol metabolism reveals a pathway optimized for membrane phase separation

链接: https://www.science.org/doi/abs/10.1126/sciadv.adu7190?af=R

期刊: bioRxiv Subject Collection: Bioinformatics

标题: 开发一种基于基因组序列和人工智能的流感病毒风险评估计算框架

英文标题: Development a computational framework for risk evaluation of emerging flu viruses based on genomic sequences and AI

链接: https://www.biorxiv.org/content/10.1101/2025.04.18.649608v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: 嵌合参考面板用于基因组推断

英文标题: Chimeric Reference Panels for Genomic Imputation

链接: https://www.biorxiv.org/content/10.1101/2025.04.22.648973v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: ShinyCell2:一个用于简单和可共享的空间、峰值基础和多组学单细胞数据可视化的扩展库

英文标题: ShinyCell2: An extended library for simple and sharable visualisation of spatial, peak-based and multi-omic single-cell data

链接: https://www.biorxiv.org/content/10.1101/2025.04.22.650045v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: 从阵列突变筛选中获得蛋白质组突变-表型联系机制见解

英文标题: Mechanistic Insights into Proteomic Mutation-Phenotype Linkages from Tiling Mutagenesis Screens

链接: https://www.biorxiv.org/content/10.1101/2025.04.17.649336v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: 精细调整蛋白质语言模型,解锁了代表性不足的病毒蛋白质组的潜力

英文标题: Fine-Tuning Protein Language Models Unlocks the Potential of Underrepresented Viral Proteomes

链接: https://www.biorxiv.org/content/10.1101/2025.04.17.649224v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: MTBseq-nf:通过MTBseq流程的用户友好Nextflow包装,实现可扩展结核病基因组学“大数据”分析

英文标题: MTBseq-nf: Enabling Scalable Tuberculosis Genomics “Big Data” Analysis through a User-Friendly Nextflow Wrapper for MTBseq pipeline

链接: https://www.biorxiv.org/content/10.1101/2025.04.17.649337v1?rss=1

期刊: bioRxiv Subject Collection: Bioinformatics

标题: EasyMultiProfiler:一种高效的微生物组研究多组学数据整合与分析工作流程

英文标题: EasyMultiProfiler: An Efficient Multi-Omics Data Integration and Analysis Workflow for Microbiome Research

链接: https://www.biorxiv.org/content/10.1101/2025.04.17.649266v1?rss=1