2025-08-15-14_articles_updated

期刊: Nature Communications

标题: 一种以吡咯并苯并噻二唑为载体的、针对人源化间变性淋巴瘤激酶（ALK）的抗体-药物偶联物在表达ALK的癌症中表现出疗效

英文标题: A humanized anaplastic lymphoma kinase (ALK)-directed antibody-drug conjugate with pyrrolobenzodiazepine payload demonstrates efficacy in ALK-expressing cancers

链接: https://www.nature.com/articles/s41467-025-62979-1

期刊: Nature Aging

标题: 免疫系统为衰老提供了一扇窗户。

英文标题: The immune system offers a window into aging

链接: https://www.nature.com/articles/s43587-025-00948-5

期刊: Nature Aging

标题: 免疫监测衰老细胞在衰老和疾病中的作用

英文标题: Immune surveillance of senescent cells in aging and disease

链接: https://www.nature.com/articles/s43587-025-00910-5

期刊: Nature Aging

标题: 衰老重塑适应性免疫系统从治疗者到破坏者的角色

英文标题: Aging reshapes the adaptive immune system from healer to saboteur

链接: https://www.nature.com/articles/s43587-025-00906-1

期刊: Nature Aging

标题: 持续免疫年轻化会增加老年宿主患自身免疫病的风险

英文标题: Sustained immune youth risks autoimmune disease in the aging host

链接: https://www.nature.com/articles/s43587-025-00919-w

期刊: Nature Aging

标题: 代谢调控免疫衰老

英文标题: Metabolic regulation of immunological aging

链接: https://www.nature.com/articles/s43587-025-00921-2

期刊: Nature Aging

标题: 恢复固有组织巨噬细胞以对抗衰老和癌症

英文标题: Restoring resident tissue macrophages to combat aging and cancer

链接: https://www.nature.com/articles/s43587-025-00898-y

期刊: Computational biology and bioinformatics : nature.com subject feeds

标题: 精心制作的CYP450相互作用数据集：涵盖大多数I期药物代谢

英文标题: Curated CYP450 Interaction Dataset: Covering the Majority of Phase I Drug Metabolism

链接: https://www.nature.com/articles/s41597-025-05753-8

期刊: Computational biology and bioinformatics : nature.com subject feeds

标题: HIBRID：基于组织学风险分层结合深度学习和ctDNA的结直肠癌

英文标题: HIBRID: histology-based risk-stratification with deep learning and ctDNA in colorectal cancer

链接: https://www.nature.com/articles/s41467-025-62910-8

期刊: Nature Reviews Drug Discovery

标题: 从基因猎人到药物猎人

英文标题: From gene hunter to drug hunter

链接: https://www.nature.com/articles/d41573-025-00139-2

期刊: AAAS: Science: Table of Contents

标题: 利用物理信息深度学习预测国家点火装置的聚变点火

英文标题: Predicting fusion ignition at the National Ignition Facility with physics-informed deep learning

链接: https://www.science.org/doi/abs/10.1126/science.adm8201?af=R

期刊: AAAS: Science: Table of Contents

标题: 使用生成深度学习进行蛋白质平衡集合的可扩展模拟

英文标题: Scalable emulation of protein equilibrium ensembles with generative deep learning

链接: https://www.science.org/doi/abs/10.1126/science.adv9817?af=R

期刊: Latest headlines from BMJ

标题: 注意缺陷多动障碍药物治疗方法与自杀行为、物质滥用、意外伤害、交通事故和犯罪风险：目标试验的模拟

英文标题: ADHD drug treatment and risk of suicidal behaviours, substance misuse, accidental injuries, transport accidents, and criminality: emulation of target trials

链接: http://www.bmj.com/content/390/bmj-2024-083658.short?rss=1

期刊: medrxiv Subject Collection: Health Informatics

标题: 整合机器学习管道用于阿尔茨海默病和帕金森病的多模态生物标志物预测：神经诊断框架的一部分

英文标题: Integrating Machine Learning Pipelines for Multimodal Biomarker Prediction in Alzheimer and Parkinson Disease: A Component of the Neurodiagnoses Framework

链接: http://medrxiv.org/cgi/content/short/2025.08.13.25333561v1?rss=1