2025-09-16-14_articles_updated
Published:
期刊: Nature Methods
标题: 基于单细胞和空间组学测序数据中DNA拷贝数检测癌症亚克隆
英文标题: Cancer subclone detection based on DNA copy number in single-cell and spatial omic sequencing data
链接: https://www.nature.com/articles/s41592-025-02773-5
期刊: Nature Methods
标题: 使用GHIST的深度学习从组织学中获得单细胞分辨率的基因表达空间分布
英文标题: Spatial gene expression at single-cell resolution from histology using deep learning with GHIST
链接: https://www.nature.com/articles/s41592-025-02795-z
期刊: Nature Communications
标题: 一种通过基于结构的药物设计确定的聚环骨架能有效抑制人P2X7受体
英文标题: A polycyclic scaffold identified by structure-based drug design effectively inhibits the human P2X7 receptor
链接: https://www.nature.com/articles/s41467-025-62643-8
期刊: Nature Aging
标题: 血液DNA甲基化测试揭示了每个器官系统衰老的速度
英文标题: A blood DNA methylation test reveals how quickly each organ system is aging
链接: https://www.nature.com/articles/s43587-025-00959-2
期刊: Nature Aging
标题: 系统老龄化：一项单一血液甲基化测试，用于量化11个生理系统中的老化异质性
英文标题: Systems Age: a single blood methylation test to quantify aging heterogeneity across 11 physiological systems
链接: https://www.nature.com/articles/s43587-025-00958-3
期刊: Computational biology and bioinformatics : nature.com subject feeds
标题: 利用GHIST的深度学习从组织学中获得单细胞分辨率的基因表达空间分布
英文标题: Spatial gene expression at single-cell resolution from histology using deep learning with GHIST
链接: https://www.nature.com/articles/s41592-025-02795-z
期刊: Computational biology and bioinformatics : nature.com subject feeds
标题: 一项血液DNA甲基化测试揭示了每个器官系统老化速度的快慢。
英文标题: A blood DNA methylation test reveals how quickly each organ system is aging
链接: https://www.nature.com/articles/s43587-025-00959-2
期刊: Computational biology and bioinformatics : nature.com subject feeds
标题: 基于单细胞和空间组学测序数据中DNA拷贝数检测癌症亚克隆
英文标题: Cancer subclone detection based on DNA copy number in single-cell and spatial omic sequencing data
链接: https://www.nature.com/articles/s41592-025-02773-5
期刊: Computational biology and bioinformatics : nature.com subject feeds
标题: 系统时代：一次血液甲基化测试即可量化11个生理系统中衰老异质性
英文标题: Systems Age: a single blood methylation test to quantify aging heterogeneity across 11 physiological systems
链接: https://www.nature.com/articles/s43587-025-00958-3
期刊: Computational biology and bioinformatics : nature.com subject feeds
标题: 街区上的新微生物：利用人类肿瘤测序数据研究微生物的挑战与机遇
英文标题: The new microbiome on the block: challenges and opportunities of using human tumor sequencing data to study microbes
链接: https://www.nature.com/articles/s41592-025-02807-y
期刊: Computational biology and bioinformatics : nature.com subject feeds
标题: 基于图变换器生成对抗网络的靶向特异性从头设计药物候选分子
英文标题: Target-specific de novo design of drug candidate molecules with graph-transformer-based generative adversarial networks
链接: https://www.nature.com/articles/s42256-025-01082-y
期刊: Nature Genetics
标题: 通过数据链接和跨生物库努力实现我们未来健康的全部潜力
英文标题: Realizing the full potential of Our Future Health through data linkage and trans-biobank efforts
链接: https://www.nature.com/articles/s41588-025-02327-7
期刊: bioRxiv Subject Collection: Bioinformatics
标题: 评估用于生物医学事实核查的语言模型：癌症变异解释验证的基准数据集
英文标题: Evaluating Language Models for Biomedical Fact-Checking: A Benchmark Dataset for Cancer Variant Interpretation Verification
链接: https://www.biorxiv.org/content/10.1101/2025.09.10.675443v1?rss=1
期刊: bioRxiv Subject Collection: Bioinformatics
标题: 疾病特异性变异致病性预测利用多模态生物医学语言模型
英文标题: Disease-specific variant pathogenicity prediction using multimodal biomedical language models
链接: https://www.biorxiv.org/content/10.1101/2025.09.09.675184v1?rss=1