2026-04-16-8_articles_updated

期刊: Nature

标题: 利用 PerturbFate 绘制黑色素瘤药物耐药性的汇聚调控因子

英文标题: Mapping convergent regulators of melanoma drug resistance by PerturbFate

链接: https://www.nature.com/articles/s41586-026-10367-0

期刊: Nature

标题: 基因编辑细胞的分子表征揭示了共同的耐药机制

英文标题: Molecular profiling of gene-edited cells reveals shared drug-resistance mechanisms

链接: https://www.nature.com/articles/d41586-026-01181-9

期刊: Nature Medicine

标题: 乙酰化Tau-174脑脊液生物标志物区分额颞叶变性患者中的TDP-43与tau病理

英文标题: An acetylated Tau-174 CSF biomarker discriminates between TDP-43 and tau pathology in patients with frontotemporal lobar degeneration

链接: https://www.nature.com/articles/s41591-026-04341-6

期刊: Nature Genetics

标题: 大脑衰老过程中的染色质重塑

英文标题: Chromatin remodeling during brain aging

链接: https://www.nature.com/articles/s41588-026-02590-2

期刊: AAAS: Science Advances: Table of Contents

标题:

英文标题: Multitissue, multi–time point transcriptomic atlas of aging in mice and rats

链接: https://www.science.org/doi/abs/10.1126/sciadv.ady8401?af=R

期刊: AAAS: Science Advances: Table of Contents

标题: 通过自监督正交学习增强生物医学光学体积成像

英文标题: Enhancing biomedical optical volumetric imaging via self-supervised orthogonal learning

链接: https://www.science.org/doi/abs/10.1126/sciadv.ady9194?af=R

期刊: AAAS: Science Advances: Table of Contents

标题: 利用强化学习引导半柔性分子扩散模型进行基于结构的药物设计

英文标题: Steering semi-flexible molecular diffusion model for structure-based drug design with reinforcement learning

链接: https://www.science.org/doi/abs/10.1126/sciadv.ady9955?af=R

期刊: JAMA Network Open New Online

标题: 预测乳房切除术后乳房重建并发症的机器学习模型

英文标题: Machine Learning Model to Predict Postmastectomy Breast Reconstruction Complications

链接: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2847773