Talks and presentations

Transcriptome-based drug repositioning for COVID-19

August 26, 2021

Conference proceedings talk, World biological science and technology conference 2021 BioST virtual 2021, virtual

Cogena-based drug repositioning is less computationally intensive than docking methods.

Co-expressed gene-set enrichment analysis for drug repositioning with examples of psoriasis and periodontal diseases

October 13, 2019

Conference proceedings talk, The 4th Big Data Forum for Life and Health Sciences 2019, Beijing

Cogena is a tool of gene set enrichment analysis for co-expression genes.
Cogena can be used in drug repositioning and discovering the MoA of drugs, illustrated with two disease, psoriasis and periodontal diseases, examples.
Cogena can be used to discovery similar drugs or treatable diseases (if the input of cogena is drug signature)
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Drug repositioning based on coexpressed gene-set enrichment analysis (cogena)

July 12, 2015

Conference proceedings talk, European Bioconductor Developers' Conference 2015, Cambridge

introduce cogena package and the main functions
In a Psoriasis example, cogena retrieves disease relevant mechanisms and drugs
Cogena is a powerful Bioconductor package for drug repositioning and drug mode of action discovery
Cogena is available from Bioconductor or https://github.com/zhilongjia/cogena
Reproduciable research: http://zhilongjia.github.io/psoriasis/
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